Ningbo Distant Chemicals (DST) Co., Ltd.
Ningbo Free Trade Zone Yuanfang Biochemicals Co.,Ltd.

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Intermediate

Edoxaban and their advanced intermediates

No.	Products Name	CAS No.
1	tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate 99%	1210348-34-7
2	tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate 98.5%	365998-36-3
3	(1S,3R,4R)-3-(Boc-aMino)-4-hydroxy-cyclohexanecarboxylic acid ethyl ester	365997-33-7
4	(1S,4S,5S)-4-bromo-6-oxabicyclo<3.2.1>octan-7-one 97%	139893-81-5
5	5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxylic acid,hydrochloride 98.5%	720720-96-7
6	Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride 98.5%	1243308-37-3

Products Name

tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate 99%
CAS No.:1210348-34-7

tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate 98.5%
CAS No.:365998-36-3

(1S,3R,4R)-3-(Boc-aMino)-4-hydroxy-cyclohexanecarboxylic acid ethyl ester
CAS No.:365997-33-7

(1S,4S,5S)-4-bromo-6-oxabicyclo<3.2.1>octan-7-one 97%
CAS No.:139893-81-5

5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxylic acid,hydrochloride 98.5%
CAS No.:720720-96-7

Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride 98.5%
CAS No.:1243308-37-3

Sparsentan and their advanced intermediates

No.	Products Name	CAS No.
1	3-Amino-4,5-dimethylisoxazole 99%	13999-39-8
2	(2-(N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)sulfamoyl)phenyl)boronic acid 98%	415697-58-4
3	N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide	415697-56-2
4	2-broMo-N-(4,5-diMethylisoxazol-3-yl)benzenesulfonaMide 98%	195447-72-4
5	2-bromo-N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)benzenesulfonamide 98%	415697-57-3
6	4-bromo-3-ethoxymethyl-benzoic acid ethyl ester 99%	948349-66-4

Products Name

3-Amino-4,5-dimethylisoxazole 99%
CAS No.:13999-39-8

(2-(N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)sulfamoyl)phenyl)boronic acid 98%
CAS No.:415697-58-4

N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide
CAS No.:415697-56-2

2-broMo-N-(4,5-diMethylisoxazol-3-yl)benzenesulfonaMide 98%
CAS No.:195447-72-4

2-bromo-N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)benzenesulfonamide 98%
CAS No.:415697-57-3

4-bromo-3-ethoxymethyl-benzoic acid ethyl ester 99%
CAS No.:948349-66-4

Adagrasib and their advanced intermediates

No.	Products Name	CAS No.
1	tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate 99%	916420-27-4

Products Name

tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate 99%
CAS No.:916420-27-4

Iptacopan and their advanced intermediates

No.	Products Name	CAS No.
1	methyl4-((2S,4S)-4-ethoxypiperidin-2-yl)benzoate	1644667-61-7
2	tert-Butyl 4-formyl-5-methoxy-7-methyl-1H-indole-1-carboxylate	1481631-51-9
3	4-((2S,4S)-4-ethoxy-1-((tert-butoxycarbonyl-5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoicacid	2803364-77-2
4	4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoicacid	1644670-37-0

Products Name

methyl4-((2S,4S)-4-ethoxypiperidin-2-yl)benzoate
CAS No.:1644667-61-7

tert-Butyl 4-formyl-5-methoxy-7-methyl-1H-indole-1-carboxylate
CAS No.:1481631-51-9

4-((2S,4S)-4-ethoxy-1-((tert-butoxycarbonyl-5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoicacid
CAS No.:2803364-77-2

4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoicacid
CAS No.:1644670-37-0

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